Gene information
Official symbol MIR145
Official full name microRNA 145
Gene type microRNA
Chromosome5q32
Alias symbolhsa-mir-145; MIR-145
Previous symbolMIRN145
Gene familyMicroRNAs
Resources
Entrez Gene 406937
HGNC HGNC:31532
Ensembl ENSG00000276365
UCSC uc063iom.1
GO terms: 93 records
GO Description Category LogP Number of genes Detail
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0003729 mRNA binding GO Molecular Functions -83.3296105 82 More
GO:0003730 mRNA 3'-UTR binding GO Molecular Functions -66.9774057 54 More
GO:0006417 regulation of translation GO Biological Processes -24.5257987 35 More
GO:0006937 regulation of muscle contraction GO Biological Processes -20.8046481 43 More
GO:0006940 regulation of smooth muscle contraction GO Biological Processes -12.9613663 21 More
GO:0007517 muscle organ development GO Biological Processes -15.8908392 49 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0010611 regulation of cardiac muscle hypertrophy GO Biological Processes -13.5611908 22 More
GO:0010614 negative regulation of cardiac muscle hypertrophy GO Biological Processes -8.32112795 7 More
GO:0010656 negative regulation of muscle cell apoptotic process GO Biological Processes -14.6475350 20 More
GO:0010660 regulation of muscle cell apoptotic process GO Biological Processes -26.1774267 35 More
GO:0010662 regulation of striated muscle cell apoptotic process GO Biological Processes -17.3771355 22 More
GO:0010664 negative regulation of striated muscle cell apoptotic process GO Biological Processes -10.4011700 8 More
GO:0010665 regulation of cardiac muscle cell apoptotic process GO Biological Processes -17.8825743 22 More
GO:0010667 negative regulation of cardiac muscle cell apoptotic process GO Biological Processes -10.6601979 8 More
GO:0010712 regulation of collagen metabolic process GO Biological Processes -14.4967625 19 More
GO:0014741 negative regulation of muscle hypertrophy GO Biological Processes -8.77845673 13 More
GO:0014743 regulation of muscle hypertrophy GO Biological Processes -14.1608908 23 More
GO:0016441 post-transcriptional gene silencing GO Biological Processes -100 124 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0017148 negative regulation of translation GO Biological Processes -31.7864246 33 More
GO:0030029 actin filament-based process GO Biological Processes -9.62516039 61 More
GO:0030036 actin cytoskeleton organization GO Biological Processes -5.67075265 47 More
GO:0030111 regulation of Wnt signaling pathway GO Biological Processes -7.94227486 39 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030336 negative regulation of cell migration GO Biological Processes -30.9008082 37 More
GO:0030371 translation repressor activity GO Molecular Functions -100 82 More
GO:0031047 gene silencing by RNA GO Biological Processes -100 125 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032653 regulation of interleukin-10 production GO Biological Processes -10.1959901 18 More
GO:0032965 regulation of collagen biosynthetic process GO Biological Processes -13.1192794 17 More
GO:0034248 regulation of cellular amide metabolic process GO Biological Processes -28.1662419 40 More
GO:0034249 negative regulation of cellular amide metabolic process GO Biological Processes -35.7644618 37 More
GO:0035194 post-transcriptional gene silencing by RNA GO Biological Processes -100 124 More
GO:0035195 miRNA-mediated gene silencing GO Biological Processes -100 124 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035278 miRNA-mediated gene silencing by inhibition of translation GO Biological Processes -46.1099674 32 More
GO:0036166 phenotypic switching GO Biological Processes -7.90572347 4 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042692 muscle cell differentiation GO Biological Processes -15.1559811 45 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0043502 regulation of muscle adaptation GO Biological Processes -16.8828965 29 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0045182 translation regulator activity GO Molecular Functions -97.0300828 82 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0048644 muscle organ morphogenesis GO Biological Processes -13.8992054 24 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048662 negative regulation of smooth muscle cell proliferation GO Biological Processes -21.7509412 30 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0051147 regulation of muscle cell differentiation GO Biological Processes -17.2781401 19 More
GO:0051149 positive regulation of muscle cell differentiation GO Biological Processes -18.0749983 16 More
GO:0051150 regulation of smooth muscle cell differentiation GO Biological Processes -12.3730388 10 More
GO:0051152 positive regulation of smooth muscle cell differentiation GO Biological Processes -12.3879234 8 More
GO:0051271 negative regulation of cellular component movement GO Biological Processes -29.9238399 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051898 negative regulation of protein kinase B signaling GO Biological Processes -8.06132628 15 More
GO:0060415 muscle tissue morphogenesis GO Biological Processes -13.8643925 23 More
GO:0060537 muscle tissue development GO Biological Processes -18.3336784 54 More
GO:0060828 regulation of canonical Wnt signaling pathway GO Biological Processes -5.69122875 29 More
GO:0061061 muscle structure development GO Biological Processes -23.2569142 77 More
GO:0070372 regulation of ERK1 and ERK2 cascade GO Biological Processes -38.4320790 79 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0090263 positive regulation of canonical Wnt signaling pathway GO Biological Processes -2.20870076 11 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1903231 mRNA base-pairing post-transcriptional repressor activity GO Molecular Functions -100 82 More
GO:1905063 regulation of vascular associated smooth muscle cell differentiation GO Biological Processes -11.0911570 8 More
GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation GO Biological Processes -9.45869795 6 More
GO:1905207 regulation of cardiocyte differentiation GO Biological Processes -9.12694220 13 More
GO:1905209 positive regulation of cardiocyte differentiation GO Biological Processes -9.78130162 11 More
GO:2000112 regulation of cellular macromolecule biosynthetic process GO Biological Processes -24.0725356 37 More
GO:2000113 negative regulation of cellular macromolecule biosynthetic process GO Biological Processes -32.997895 35 More
GO:2000146 negative regulation of cell motility GO Biological Processes -30.256132 37 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05206 MicroRNAs in cancer KEGG Pathway -100 81 More
Related studies: 6 records
Molecular factor Omics type Application Objective MI type Reference
hsa-miR-145-5p transcriptomics medium predictor cardiovascular death[prognosis (bad)] acute ST elevation myocardial infarction Dong YM et al. Scand J Clin Lab Invest. 2015
hsa-miR-145-5p transcriptomics medium predictor major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Dong YM et al. Scand J Clin Lab Invest. 2015
hsa-miR-145-5p transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Zhang M et al. Chin Med J (Engl). 2017
hsa-miR-145-3p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Xue S et al. Front Physiol. 2019
hsa-miR-145-3p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Xue S et al. Front Physiol. 2019
hsa-miR-145-5p transcriptomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Fan PC et al. J Transl Med. 2019
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